Table 4 Characteristic step length for WT-PRE and WT-POST splenocytes along the negative x direction. For both groups of splenocytes we compare the mean value of negative Δx obtained by the log-normal fit with the experimental average and the standard deviation σx with the experimental value

From: Cancer-driven dynamics of immune cells in a microfluidic environment

Negative branch

〈Δx〉 [μm]

σx [μm]

σx,exp [μm]

Δx WT-PRE

6.2 ± 1.9

8.0 ± 0.5

3.2 ± 0.4

5.0 ± 0.5

Δx WT-POST

6.1 ± 1.8

6.5 ± 0.2

3.0 ± 0.7

4.2 ± 0.2

  1. Within the experimental error, compatibility among data and averages returned from the inferred log-normal distribution for the step lengths of WT dynamics along the y direction is achieved. Beyond contributing to confirm the correctness of the inferred distribution (as this returns observable's averages in agreement with data), further information can be obtained by this analysis: indeed, despite the log-normal shape still obeys CLT, it is the slower distribution still converging under CLT constraints. This implies that, despite a characteristic scale for the jump can still be defined, single step violations from the average behavior are expected to appear much more frequently and this, in turn, may suggest full activation of heterogenous sub-populations within splenocytes (see Observable One tools).
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