Figure 4 | Scientific Reports

Figure 4

From: Unglycosylated recombinant human glutathione peroxidase 3 mutant from Escherichia coli is active as a monomer

Figure 4

Comparison between rhGPx3 mutant and U46C GPx4 mutant (PDB entry 2OBI).

(a). The superposition of rhGPx3 mutant (orange) and U46C GPx4 mutant (green). The catalytic tetrad consisting of Sec(Cys), Gln, Trp and Asn is labeled. (b). The electrostatic surface potential of rhGPx3 mutant. (c). The electrostatic surface potential of U46C GPx4 mutant. The red denotes negative electrostatic potential and the blue denotes positive electrostatic potential. Potential isocontours are shown at +3 kT/e (blue) and −3 kT/e (red).The circles in panels B and C indicate oligomerization loop.

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