Table 2 Distribution of genotypes of XPG Asp1104His and their associations with risk of colorectal cancer
Gentypes | Cases(n = 878) n/% | controls(n = 884) n/% | Crude OR(95%CI) | Adjusted OR(95%CI)* | P | ||
---|---|---|---|---|---|---|---|
Asp/Asp | 286 | 32.6 | 355 | 40.2 | 1.00(reference) | 1.00(reference) | |
Asp/His | 459 | 52.3 | 405 | 45.8 | 1.41(1.15–1.73) | 1.41(1.15–1.74) | 0.001 |
His/His | 133 | 15.1 | 124 | 14.0 | 1.33(1.00–1.78) | 1.34(1.00–1.79) | 0.048 |
His/His +Asp/His | 592 | 67.4 | 529 | 59.8 | 1.39(1.14–1.69) | 1.40(1.15–1.70) | <0.001 |
His allele | 725 | 52.6 | 653 | 47.4 | 1.20(1.05–1.37) | 0.008 |