Table 2 Distribution of genotypes of XPG Asp1104His and their associations with risk of colorectal cancer

From: Association study between XPG Asp1104His polymorphism and colorectal cancer risk in a Chinese population

Gentypes

Cases(n = 878) n/%

controls(n = 884) n/%

Crude OR(95%CI)

Adjusted OR(95%CI)*

P

Asp/Asp

286

32.6

355

40.2

1.00(reference)

1.00(reference)

 

Asp/His

459

52.3

405

45.8

1.41(1.15–1.73)

1.41(1.15–1.74)

0.001

His/His

133

15.1

124

14.0

1.33(1.00–1.78)

1.34(1.00–1.79)

0.048

His/His +Asp/His

592

67.4

529

59.8

1.39(1.14–1.69)

1.40(1.15–1.70)

<0.001

His allele

725

52.6

653

47.4

1.20(1.05–1.37)

 

0.008

  1. *Adjusted for age, sex and smoking and drinking status in logistic regression model.