Table 5 Meta-analysis of the association between the XPG Asp1104His polymorphism and colorectal cancer risk
His/His vs. Asp/Asp | Asp/His vs. Asp/Asp | His/His + Asp/His vs. Asp/Asp | His/His vs. Asp/His + Asp/Asp | ||||||
|---|---|---|---|---|---|---|---|---|---|
Stratification | No. case/control | OR (95%CI) | P/P he | OR (95%CI) | P/P he | OR (95%CI) | P/P he | OR (95%CI) | P/P he |
Total | 2649/2848 | 1.24(1.03–1.47) | 0.020/0.562 | 0.85(0.69–1.05) | 0.127/0.303 | 1.35(1.20–1.5) | 0/0.473 | 0.97(0.83–1.14) | 0.750/0.430 |
Ethnicity | |||||||||
Asian | 1906/1969 | 1.28(1.05,1.55) | 0.012/0.473 | 1.49(1.29,1.73) | 0/0.418 | 1.44(1.25,1.65) | 0/0.636 | 0.98(0.83,1.16) | 0.285/0.797 |
Caucasian | 743/879 | 0.97(0.59,1.58) | 0.900/0.372 | 1.19(0.96,1.48) | 0.109/0.397 | 1.16(0.94,1.44) | 0.147/0.718 | 0.92(0.57,1.48) | 0.720/0.262 |
