Figure 1 | Scientific Reports

Figure 1

From: A Palindromic Motif in the −2084 to −2078 Upstream Region is Essential for ABCA12 Promoter Function in Cultured Human Keratinocytes

Figure 1

Position −2980 to position −1994 of the ABCA12 gene has promoter activity.

Dual luciferase assay was performed using firefly luciferase reporter vectors that contain −2980/+190, −1994/+190 or −1039/+190 fragments of the ABCA12 gene. The culture medium contained either 0.06 mM or 1.2 mM calcium. The promoter activities are normalized using the empty vector as a standard. The bars represent the standard deviation (n = 3). *P < 0.01 compared with the −2980/+190 fragment.

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