Figure 2 | Scientific Reports

Figure 2

From: Interactions of CaMKII with dopamine D2 receptors: roles in levodopa-induced dyskinesia in 6-hydroxydopamine lesioned Parkinson's rats

Figure 2

The CaMKIIα binding motif in D2R-IL3.

(A) Binding of CaMKIIα to GST-fusion proteins derived from D2R-IL3. (B) Binding of CaMKIIα to GST-fusion proteins derived from D2R-IL3 and D3R-IL3. Note that Q345-Q374 fragments showed the ability to bind to CaMKIIα. (C) Amino acid sequence of D2R-IL(Q345-Q374). In vitro binding assays were carried out with purified recombinant proteins. Bound CaMKIIα was visualized by immunoblots (IB) of the eluted proteins using a specific antibody.

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