Figure 7 | Scientific Reports

Figure 7

From: PINK1-mediated Phosphorylation of Miro Inhibits Synaptic Growth and Protects Dopaminergic Neurons in Drosophila

Figure 7

DMiroS182A,S324A,T325A Does Not Cause Muscle Degeneration or Swollen Mitochondria.

(A) Light microscopic images of thick sections show indirect flight muscles and (B) TEM images of thin sections show mitochondria inside muscle cells, performed on thoraces of adult flies as indicated 5 days after eclosion. (C) Schematic representation of the regulatory mechanisms by which PINK1 and Miro control cellular functions. Blue boxes in Miro indicate GTPase domains and green boxes are EF-hands. Scale bars: (A) 10 μm; (B) 0.5 μm.

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