Figure 1
Schematic diagram of our novel lateral flow cotton-based diagnostic device.
This cotton-based device was designed for the diagnosis in a buffer system or in a clinical system. (A) Our cotton-based diagnostic device contains three parts: sample/reaction zone test pad (a single-layer membrane, Whatman chromatography paper), flow channel of cotton hydrophobic and hydrophilic layer (a cotton membrane, Shiseido cleansing cotton) and a background packaging substrate (a thick plastic material lamination film). (B) Top view and cross section show the distance of each test pad (1 cm) and sample flow direction (orange line). (C) This lateral flow-based device has been shown for the diagnosis of BSA, nitrite and uric acid assays in a buffer system. Photographic evidence of our device test pads (top view) showing negative control and experimental example after we immobilized BSA, nitrite and uric acid assays on the test pad.
