Table 1 Associations between the selected SNPs and gastric cancer risk
SNPs | Genetic model | Genotype | Cases | Controls | P a | Crude OR (95% CI) | Adjusted OR (95% CI)b |
|---|---|---|---|---|---|---|---|
rs6976789 | Codominant | CC | 481 | 653 | 0.100 | 1.00 (reference) | 1.00 (reference) |
CT | 255 | 278 | 1.25 (1.01–1.53) | 1.25 (1.02–1.54) | |||
TT | 17 | 18 | 1.28 (0.66–2.51) | 1.28 (0.65–2.51) | |||
Dominant | CC | 481 | 653 | 0.032 | 1.00 (reference) | 1.00 (reference) | |
CT+TT | 272 | 296 | 1.25 (1.02–1.53) | 1.25 (1.02–1.53) | |||
Recessive | CC+CT | 736 | 931 | 0.602 | 1.00 (reference) | 1.00 (reference) | |
TT | 17 | 18 | 1.20 (0.61–2.33) | 1.19 (0.61–2.32) | |||
rs2235749 | Codominant | AA | 564 | 690 | 0.545 | 1.00 (reference) | 1.00 (reference) |
AG | 170 | 236 | 0.88 (0.70–1.11) | 0.89 (0.71–1.11) | |||
GG | 19 | 23 | 1.01 (0.55–1.87) | 1.01 (0.54–1.87) | |||
Dominant | AA | 564 | 690 | 0.308 | 1.00 (reference) | 1.00 (reference) | |
AG+GG | 189 | 259 | 0.89 (0.72–1.11) | 0.90 (0.72–1.12) | |||
Recessive | AA+AG | 734 | 926 | 0.900 | 1.00 (reference) | 1.00 (reference) | |
GG | 19 | 23 | 1.04 (0.56–1.93) | 1.04 (0.56–1.92) |
