Figure 7
From: Regulation of synaptic plasticity and cognition by SUMO in normal physiology and Alzheimer's disease
SUMOylation is dysregulated in human Alzheimer's disease hippocampal tissue.
SUMOylation is decreased in AD. Representative SUMO2/3 western blot with post-mortem hippocampal formation tissue from AD and control patients. Starred bracket indicates the analyzed high molecular weight region exhibiting the most significant reduction of SUMO conjugates. Control and AD n = 6 each; *p = 0.015. Data presented as means ± SEM, % of control group. See also Supplementary Figure S7, Table S1.
