Figure 7
From: RILP interacts with HOPS complex via VPS41 subunit to regulate endocytic trafficking
The effects of overexpressing VPS41(428–855) (VPS41CT) on EGF-Rhodamine endocytosis and degradation.
(A). over-expressing VPS41CT delayed endocytic clearance of EGF-Rhodamine similar to the effect of shRNA-VPS41. (B). EGF-Rhodamine accumulated vesicles were co-localized with late endosomal/lysosomal markers CD63 and Lamp1 after 60 min endocytosis in cells expressing VPS41CT. Bar = 20 μm.
