Table 1 Baseline characteristics of men with newly diagnosed hypertension according to uric acid median
Parameters | Low UA (n = 256) | High UA (n = 256) | P value |
|---|---|---|---|
Age (years) | 46.8 ± 7.8 | 46.9 ± 7.8 | 0.843 |
Male (%) | 117(45.7%) | 201(78.5%) | 0.000 |
Smoking, yes | 25(9.8%) | 51(19.9%) | 0.001 |
Body weight index (kg/m2) | 25.6 ± 3.7 | 26.2 ± 3.1 | 0.049 |
Diabetes mellitus (%) | 23(9.0%) | 16(6.3%) | 0.244 |
Systolic blood pressure (mmHg) | 152.6 ± 12.1 | 152.4 ± 11.7 | 0.795 |
Diastolic blood pressure (mmHg) | 99.7 ± 8.9 | 100.2 ± 8.7 | 0.532 |
Uric acid (μmol/L) | 303.6 ± 28.2 | 382.5 ± 27.5 | 0.000 |
Creatinine (μmol/L) | 66.9 ± 12.9 | 73.0 ± 12.4 | 0.000 |
eGFR (mL/min/1.73 m2) | 105.6 ± 24.7 | 104.5 ± 24.6 | 0.490 |
ACR (mg/g) | 34.7 ± 41.7 | 40.9 ± 48.4 | 0.120 |
TC (mmol/L) | 5.1 ± 0.9 | 5.2 ± 0.8 | 0.502 |
TG (mmol/L) | 1.8 ± 0.5 | 1.9 ± 0.6 | 0.002 |
HDL-cholesterol (mmol) | 1.1 ± 0.2 | 1.0 ± 0.2 | 0.002 |
LDL-cholesterol (mmol) | 3.1 ± 0.8 | 3.2 ± 0.8 | 0.524 |
AST (U/L) | 24.2 ± 10.4 | 26.5 ± 11.4 | 0.004 |
ALT (U/L) | 27.7 ± 22.9 | 34.1 ± 26.0 | 0.020 |
BUN (mmol/L) | 4.7 ± 1.2 | 4.9 ± 1.1 | 0.011 |
Fasting glucose (mmol/L) | 7.7 ± 2.1 | 7.3 ± 2.3 | 0.180 |
WBC count (103/mm3) | 6.4 ± 1.8 | 6.5 ± 1.7 | 0.901 |
RBC count (103/mm3) | 4.9 ± 0.4 | 5.0 ± 0.5 | 0.000 |
RDW (%) | 12.6 ± 0.8 | 12.9 ± 0.9 | 0.032 |
Plt count (103/mm3) | 238.9 ± 53.1 | 235.2 ± 53.5 | 0.548 |
CRP (mg/dL) | 2.5 ± 5.0 | 2.3 ± 4.7 | 0.758 |
Hb (g/L) | 146.5 ± 15.5 | 153.7 ± 15.5 | 0.000 |