Table 2 Nucleotide substitution rates and selection pressures for the HAdV-7d strain DG01_2011 major capsid protein genes. The mean numbers of non-synonymous (Ka) and synonymous (Ks) substitutions per site from between sequences were noted and Ka/Ks ratios were calculated. This selection pressure analysis was conducted using the Nei-Gojobori model and included nucleotide sequences from 33 hexon, 57 fiber and 19 penton base genes of HAdV-7 available from GenBank. All positions containing gaps were eliminated automatically. Evolutionary analyses were performed with MEGA 5.1.0 (http://www.megasoftware.net)
Gene | Length (bp) | No. of Sequences | Mean Non-synonymous Substitutions/site | Mean Synonymous Substitutions/site | Ka/Ks |
---|---|---|---|---|---|
Hexon | 2805 | 33 | 0.003 | 0.043 | 0.069 |
Penton base | 1635 | 19 | 0.003 | 0.025 | 0.12 |
Fiber | 978 | 57 | 0.013 | 0.053 | 0.245 |