Figure 2

Decreased expression of IL-6R on lung infiltrating CD4+CD25+Foxp-3+ T-cells in a murine model of lung cancer.
(a),(b)- Flow cytometry analysis of IL-6R in the lungs of naïve as compared to LL/2-luc-M38 injected wild-type mice (Nnaive = 10, NLL/2 = 11). a-Percentage of IL6R+CD4+ T-cells gated on lymphocytes. b- Percentage of IL-6R+cells gated on CD4+CD25+Foxp-3+ T-cells. Dot plots depict the gating strategy. Bar charts show the mean percentage of gated cells. Data are shown as mean values +/− s.e.m. using student's t-test ***P,0.001.