Figure 5
Effect of genotype and treatment on electrocardiography parameters distinguished by gender.
After 28days with or without aldo/NaCl treatment animals were anaesthetized with isoflurane and electrocardiography recordings were obtained for at least ten minutes employing an Einthoven I limb lead recording. PR interval (a, e) was measured from the beginning of the P wave to the start of the chamber complex, P duration (b, f) was defined as the time from start to end of the P wave, QRS interval (c, g) was measured from start to end of the chamber excitation and the QTc interval (d,h; time from start of the chamber excitation to the end of the chamber repolarization, heartrate corrected according to Bazette). Data are given as mean ± SEM, * p<0.05 compared to respective wildtype, # p<0.05 compared to respective control. N = 3-5 animals/group.
