Figure 6
Effect of genotype and treatment on heart rate variability distinguished by gender.
After 28 days with or without aldo/NaCl treatment animals were anaesthetized with isoflurane and electrocardiography recordings were obtained for at least ten minutes employing an Einthoven I limb lead recording, from these recordings heart rate variability was determined. SDNN (a, b), as standard deviation of RR interval of normal-to-normal intervals was analysed first. As no difference could be obtained in female animals, SD delta NN (standard deviation of averages of normal R-R intervals, c) and RMSSD (Square root of the mean of the sum of the squares of differences between adjacent NN intervals, d) was only analysed in male animals. Data are given as mean ± SEM, * p<0.05 compared to respective wildtype, # p<0.05 compared to respective control. N = 3–5 animals/group.
