Figure 7

Alteration of marker gene expression in hearts of male animals regarding genotype and treatment.
After 28 days with or without aldo/NaCl treatment animals were sacrificed, the hearts dissected and snap frozen in liquid nitrogen. Gene expression was analysed according to the -Δ/Δct- method normalizing the individual mRNA amount to 18S and the mean mRNA amount in the untreated wildtype. In each graph the Δ/Δct amount is given on the left y-axis while the corresponding fold change in expression is given on the right y-axis. Data are given as mean ± SEM, * p<0.05 compared to respective wildtype, # p<0.05 compared to respective control. N = 6–11 animals/group.