Table 2 Reaction condition optimization under the manganese acetate catalysisa

From: Selective Nickel- and Manganese-Catalyzed Decarboxylative Cross Coupling of Some α,β-Unsaturated Carboxylic Acids with Cyclic Ethers

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Entry

Additiveb

Base

T (°C)

Yield (%)

1

-

DBU

100

0

2

NBS

DBU

100

0

3

DDQ

DBU

100

3

4

BPO

DBU

100

5

5

TBHP

-

100

10

6

TBHP

TEA

100

11

7

TBHP

K2CO3

100

5

8

TBHP

DBU

25

27

9

TBHP

DBU

60

45

10

TBHP

DBU

90

77

11

TBHP

DBU

100

80

  1. aReaction condition: cinnamic acid (0.148 g, 1 mmol), catalyst (0.1 mmol, 10 mol %), additive (3 mmol), base (0.2 mmol, 20 mol %).
  2. bTBHP = tert-butyl hydroperoxide, 70% in water.
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