Figure 5
From: A Low-Noise Solid-State Nanopore Platform Based on a Highly Insulating Substrate
Discrimination of 4 different ssDNA homopolymers using quartz-substrate-based nanopore.
(a), Concatenated sets of translocation events from each homopolymer (poly-A40, poly-T40 and poly-C40) using a nanopore consisting effective thickness and diameter of 2.4 and 1.4 nm, respectively at 200 mV. (b), Normalized histogram of the residual current amplitudes, which reveal the well-characterized distribution of poly-A40 and poly-T40 and a comparatively broad distribution of poly-C40. (c), Concatenated sets of translocation events for the mixture of poly-A40 and poly-T40 homopolymers. (d), Normalized histogram of translocation events for a mixture of the homopolymers. Poly-A40 and poly-T40 exhibited values almost identical to those obtained from individual homopolymer translocation experiment.
