Table 1 Clinico-pathological characteristics and CTC enumeration of metastatic lung cancer patients. Total CTC number is enumerated in 2 mL of patient's blood sample based on DAPI+/CK+/CD 45- criteria. Secreting CTCs refer to isolated and purified CTCs with VEGF secretion in another 2 mL blood sample taken from the same patient. (SCC: Small cell carcinoma; *One microchamber contains two cells and we count as one secreting cell.)
CTC no./2 mL | |||||||
---|---|---|---|---|---|---|---|
Patient # | Age | Sex | Histology | Cancer Stage | Receiving Treatment | Total CTC no. | Secreting CTC no. |
1 | 68 | M | SCC | IV | Yes | 28 | 5 |
2 | 79 | M | SCC | IIIB | Yes | 26 | 8 |
3 | 60 | F | SCC | IV | Yes | 10 | 2* |
4 | 70 | M | SCC | IV | Yes | 35 | 12 |