Figure 7 | Scientific Reports

Figure 7

From: Levodopa/benserazide microsphere (LBM) prevents L-dopa induced dyskinesia by inactivation of the DR1/PKA/P-tau pathway in 6-OHDA-lesioned Parkinson's rats

Figure 7

Representative examples of p-tau immunofluorescence studies in sham, 6-OHDA-lesioned rats treated with vehicle, pulsatile L-dopa (20 mg/kg, bid) or LBM-M (40 mg/kg).

In 6-OHDA lesioned rats treated with L-dopa induced approximately increase in p-tau-positive neurons compared to other three group. These L-dopa-induced increases in positive neurons disappear in LBM-M group. Shown is a coronal section of the striatum from the lesioned hemisphere; ## p < 0.05 vs LID rats.

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