Figure 5
From: Nicotine exposure and transgenerational impact: a prospective study on small regulatory microRNAs
Directed acyclic graph (DAG) performed by GOrilla.
14 miRNAs that were differentially expressed in at least 2 generations were used for target prediction. Only genes belonging to enriched clusters in DAVID were used to prepare the single gene ranked list for GOrilla input as described in the text. The Graph shows the relationships among the enriched pathways targeted by miRNAs altered in response to nicotine treatment. Colors represent P-values. From white to orange/red, p-values range from >10−3 to <10−9.
