Figure 3 | Scientific Reports

Figure 3

From: Comprehensive profiling analysis of actively resorbing osteoclasts identifies critical signaling pathways regulated by bone substrate

Figure 3

Regulation of cell cycle progression and proliferation by bone substrate and itgb3.

(a) GSEA analysis showing modulation of the cell cycle progression pathway by both bone and itgb3. (b) Detailed microarray analysis of cdc7 and Cyclin B1 probe sets in cells cultured for 1, 3 and 5 days on plastic or calvaria (bone), in the presence (+RL) or absence (−RL) of RANKL.

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