Table 2 Pathway and functional analysis of gene sets regulated by bone substrate
Category | p-Value | Molecules |
|---|---|---|
Cellular Function and Maintenance | 4.65E-06 | ACAP1, ATG4C, ATM, AXL, BNIP3, CA9, CADM1, CADPS, CCL22, CLEC6A, COL5A3, CRYAB, CXCL3, DCLRE1C, DDIT4, EGR1, ERO1L, FAS, FCGR2B, FPR2, FXYD2, GATM, GHR, GNA13, ICA1, IL7R, KCNJ10, KIF5B, LAMA3, MAP1LC3A, MBP, MED1, MSR1, MT1H, MTM1, MYSM1, NDRG1, NMB, NOS3, NPY, NUCB2, NUPR1, Rps6/Rps6-ps4, SESN2, SLC12A2, SLC2A1, SLC37A4, SLC8A1, STAP2, TRIB3, WWP2, ZEB1 |
Cell Death and Survival | 1.25E-05 | ABCA3, AIM2, ALDH2, AMACR, AQP9, ARG1, ATM, AXL, BMP2, BNIP3, BUB1, CA9, CADM1, CADPS, CASP4, CCL27, CD2AP, CD300LD, Cd59a, CHST11, COL5A3, CRYAB, CTH, CXCL3, DCLRE1C, DDIT4, DSG2, DSP, EGR1, EHD3, EYA1, FAM162A, FAS, FCGR2B, FHL2, FOXK2, FSTL1, FUBP1, G2E3, GHR, GLO1, GNA13, GNAI1, GRIA3, H60a, HK2, HYOU1, IBSP, Ifi202b, IL7R, ITCH, ITGB3, JAG1, KCNJ10, KLRD1, LAMA3, LATS1, MAP1LC3A, MBD4, MBP, MED1, MPO, MSI2, MSR1, MT1H, MTM1, NDRG1, NLE1, NOS3, NPY, NSF, NUPR1, PAFAH1B2, POU2AF1, PPP2R1B, Pvr, RAI14, Rps6/Rps6-ps4, SESN2, SIK1, SLC12A2, SLC2A1, SLC8A1, STAP2, SUB1, TIA1, TIMP2, TNFRSF14, TNFRSF9, TRIB3, UCHL1, URI1, VAMP3, WASF1, WWP2, XAF1, ZEB1, ZFR |
Cellular Growth and Proliferation | 1.81E-05 | ADAMTS4, AIM2, AK4, AMACR, APOBEC1, AQP9, ARF1, ARG1, ARHGAP5, ARHGDIG, ATM, AXL, BMP2, BNIP3, BPNT1, BUB1, CA9, CACUL1, CADM1, CCDC19, CCL27, CD2AP, Cd59a, CD84, CHST11, CREB3, CRYAB, CTH, CXCL3, DCLRE1C, DFNA5, DSG2, DSP, DUSP8, EGR1, ELOVL7, EPS8, ERO1L, EYA1, FAS, FCGR2B, FHL2, FPR2, FSCN1, FXYD2, GFER, GHR, GNA13, GNAI1, GRIA3, H60a, HAO1, HK2, IBSP, Ifi202b, Ifi204, IGF2BP3, IL7R, ITCH, ITGB3, JAG1, KLRD1, LAMA3, LATS1, MAPRE1, MBP, MED1, MSI2, MSR1, MT1H, NDRG1, NMB, NOS3, NPY, NUCB2, NUPR1, P4HA2, PLS3, POU2AF1, PPP2R1B, PTX3, Pvr, QPCT, RHOU, SIK1, SLC12A2, SLC2A1, SLC8A1, STAP2, TIMP2, TLE6, Tmsb4x, TNFRSF14, TNFRSF9, TPM2, TRIB3, UCHL1, URI1, VLDLR, VPS39, WLS, WWP2, ZEB1 |
Cellular Movement | 2.21E-05 | AQP9, ARF1, ARG1, ARHGAP5, ATM, AXL, BMP2, C1GALT1, CA9, CADM1, CCL22, CCL27, Cd59a, CD99L2, CREB3, CRYAB, CXCL3, EGR1, ELK3, EPS8, FAS, FCGR2B, FHL2, FPR2, FSCN1, FSTL1, GNA13, GNAI1, GRIA3, ITCH, ITGB3, JAG1, LAMA3, MAPRE1, MBP, MED1, MPO, MSR1, NDRG1, NOS3, NPY, NUCB2, P4HA2, POU2AF1, PTX3, Pvr, QPCT, RAP2B, RHOU, ROPN1L, SEMA3C, SLC12A2, SLC2A1, SLC37A4, SLC8A1, STAP2, TIMP2, TLE6, Tmsb4x, TNFRSF14, TNFRSF9, USP14, VLDLR, WASF1, ZEB1 |
Amino Acid Metabolism | 2.47E-05 | GATM, NAGS, NOS3, QPCT |
