Figure 3
Particle size distributions of isolated liposome samples as measured by DLS and TRPS.
(A) DLS percent intensity by size (nm) for ExoSpin, Invitrogen, PureExo, Ultracentrifugation and Unprocessed control. (B) TRPS measurements with an NP150 pore of particle size distributions for ExoSpin (n = 1777), Invitrogen (n = 3302), PureExo (n = 0), Ultracentrifugation (n = 923) and unprocessed (n = 1312) samples respectively. Boxes indicate 25th, 50th and 75th percentile values, whiskers encapsulate 1st and 99th percentile values. (C) Modal Β± SD particle diameter for ExoSpin (n = 3), Invitrogen (n = 3), ultracentrifugation (n = 3) treated samples and the unprocessed negative control as measured by TRPS with an NP150 pore. There was no significant difference in size between any of the processed samples and the unprocessed control (p>0.05). (D) Mean Β± SD particle diameter for ExoSpin (n = 3), Invitrogen (n = 3), ultracentrifugation (n = 3) treated samples and the unprocessed negative control as measured by TRPS with an NP150 pore. There was no significant difference between any of the processed samples and the unprocessed control.
