Table 2 The relative contents of 45 identified cis-diol-containing compounds in urines of 3 types of cancer patients over healthy controls

1

5-Methyluridine

0.69 ± 0.03

0.52 ± 0.06

0.53 ± 0.04

2

6-Methyluridine

0.81 ± 0.07

0.40 ± 0.05

0.42 ± 0.04

3

Adenosine

0.99 ± 0.13

1.07 ± 0.02

1.28 ± 0.07

4

1-Methylguanosine

1.16 ± 0.01

1.40 ± 0.14

1.58 ± 0.07

5

Guanosine

2.08 ± 0.04

0.89 ± 0.00

1.98 ± 0.22

6

1-Methylinosine

1.80 ± 0.16

1.41 ± 0.10

1.92 ± 0.06

7

1-Methyladenosine

0.74 ± 0.05

3.77 ± 0.29

0.94 ± 0.07

8

N²-methylguanosine

1.33 ± 0.16

1.38 ± 0.09

1.43 ± 0.09

9

N², N²-dimethylguanosine

1.32 ± 0.09

1.23 ± 0.16

1.57 ± 0.10

10

3-Methyluridine

0.72 ± 0.05

0.91 ± 0.15

1.14 ± 0.11

11

5′-Deoxy-5′-methylthioadensine

2.04 ± 0.14

3.26 ± 0.32

2.38 ± 0.32

12

Succinyladenosine

0.89 ± 0.03

0.74 ± 0.08

0.99 ± 0.07

13

N⁶-methyladenosine

1.27 ± 0.06

1.27 ± 0.02

1.78 ± 0.15

14

Orotidine

0.85 ± 0.07

0.78 ± 0.04

0.83 ± 0.08

15

Urate-3-ribonucleoside

1.12 ± 0.11

1.21 ± 0.05

1.09 ± 0.12

16

Nicotinamide riboside

0.69 ± 0.04

1.16 ± 0.05

1.22 ± 0.10

17

n-Ribosylhistidine

0.81 ± 0.05

0.83 ± 0.05

0.75 ± 0.01

18

Cytidine

1.29 ± 0.13

1.28 ± 0.08

1.28 ± 0.09

19

Pseudouridine

1.37 ± 0.11

1.13 ± 0.04

1.37 ± 0.17

20

Uridine

1.06 ± 0.06

1.24 ± 0.06

1.10 ± 0.06

21

5-Carbamoylmethyluridine

0.76 ± 0.03

0.72 ± 0.02

0.73 ± 0.06

22

6-Hydroxyl-1,6-dihydropurine ribonucleoside

0.75 ± 0.04

1.52 ± 0.09

1.29 ± 0.05

23

1-Methyl-N²-ethylguanosine

0.73 ± 0.10

0.51 ± 0.02

0.75 ± 0.10

24

5,6-Dihydrouridine

0.53 ± 0.07

1.25 ± 0.12

0.75 ± 0.08

25

5-Methylcytidine

1.26 ± 0.07

0.56 ± 0.04

0.55 ± 0.05

26

Inosine

1.27 ± 0.13

1.26 ± 0.11

1.24 ± 0.01

27

Ribosylpyridinonecarboxamide

1.44 ± 0.11

1.61 ± 0.09

1.88 ± 0.10

28

Xanthosine

1.62 ± 0.13

1.42 ± 0.13

2.14 ± 0.14

29

8-Oxo-Guanosine

0.58 ± 0.01

1.25 ± 0.02

1.11 ± 0.05

30

3-Methylcytidine

1.29 ± 0.16

2.11 ± 0.21

0.95 ± 0.11

31

5-Methylaminomethyluridine

1.55 ± 0.15

1.05 ± 0.08

0.75 ± 0.09

32

5′-Deoxyadenosine

1.06 ± 0.09

1.07 ± 0.14

0.77 ± 0.10

33

3-Hydroxychavicol 1-glucoside

1.26 ± 0.10

1.31 ± 0.07

1.64 ± 0.12

34

5-Methylaminomethyl-2-thiouridine

1.39 ± 0.11

0.48 ± 0.05

0.005 ± 0.00

35

Uracil-5-oxyacetic acid methylester

1.75 ± 0.04

1.38 ± 0.14

1.82 ± 0.22

36

N⁴-acetylcytidine

1.61 ± 0.17

1.56 ± 0.20

1.87 ± 0.17

37

1-Ribosyl-N-acetylhistamine

2.39 ± 0.15

0.09 ± 0.01

0.16 ± 0.02

38

N⁶-threonylcarbamoyladenosine

0.57 ± 0.04

1.00 ± 0.05

1.11 ± 0.03

39

N⁶-Methyl-2-methylthioadenosine

0.98 ± 0.03

0.84 ± 0.07

1.11 ± 0.02

40

7-Methylguanosine

2.34 ± 0.07

0.55 ± 0.04

2.05 ± 0.27

41

4-((1H-imidazol-2-yl)methyl)phenol-1-glucoside

9.49 ± 1.19

0.50 ± 0.02

0.12 ± 0.01

42

N⁶-isopentenyladenosine

25.04 ± 2.18

1.01 ± 0.01

0.85 ± 0.06

43

N2,N2,7-trimethylguanosine

1.61 ± 0.15

1.71 ± 0.15

1.55 ± 0.19

44

N²,7-dimethylguanosine

0.72 ± 0.08

0.71 ± 0.07

0.90 ± 0.12

45

1-Ribosyl-N-propionylhistamine

8.90 ± 0.97

1.51 ± 0.17

3.54 ± 0.35