Table 1 Demographic and Clinical data on subjects

From: Reduced cerebrospinal fluid ethanolamine concentration in major depressive disorder

 

dMDD

rMDD

HC

Statistics

N (Male/Female)

42 (19/23)

10 (6/4)

54 (28/26)

χ2 = 0.86, df = 2, P = 0.63 1

Age, year

45.5 ± 12.2

42.9 ± 14.9

43.6 ± 15.3

F = 0.26, df = 2, P = 0.77 2

BZD, mg/day (ratio)

14.1 ± 14.4 (29/42)

12.1 ± 17.9 (7/10)

N.A.

t = 0.38, df = 50, P = 0.71, 95% CI: −8.66 to 12.63 3

AD, mg/day (ratio)

136.9 ± 131.1 (27/42)

149.4 ± 170.4 (7/10)

N.A.

t = −0.26, df = 50, P = 0.80, 95% CI: −110.72 to 85.78 3

AP, mg/day (ratio)

83.7 ± 176.2 (13/42)

56.5 ± 125.5 (3/10)

N.A.

t = 0.46, df = 50, P = 0.65, 95% CI: −91.67 to 146.14 3

HAMD-17, score

18.0 ± 7.2

4.3 ± 2.4

N.A.

t = 10.20, df = 44.93, P < 5 × 10−13, 95% CI: 9.00 to 18.36 3

Time of CSF sampling, min 4

185.2 ± 95.4

221.5 ± 111.9

172.2 ± 118.6

F = 0.89, df = 2, P = 0.42 2

Days from CSF sampling, day 5

554.9 ± 313.5

721.5 ± 276.9

479.7 ± 286.4

F = 3.01, df = 2, P = 0.054 2

  1. 1Based on the chi-squared test with exact probability.
  2. 2Based on the analysis of variance.
  3. 3Based on the t-test.
  4. 4Sampling time is expressed as minutes from 10:00 AM.
  5. 5Number of days from the lumbar puncture day to Sep 1, 2013.
  6. Abbreviations: dMDD, depressed (non-remitted) patients with major depressive disorder; rMDD, remitted patients; HC, healthy controls; HAMD-17, 17-item Hamilton Depression Rating Scale; CSF, cerebrospinal fluid; BZD, daily diazepam equivalent dose of benzodiazepine derivatives; AD, daily imipramine equivalent dose of antidepressants; AP, daily chrolpromazine equivalent dose of antipsychotics; CI, confidence interval for the difference between two means.
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