Figure 3
From: Identification of molecular signature of head and neck cancer stem-like cells
Oralspheres display higher tumorigenicity in NSG mice xenograft model.
(a) Parental and oralspheres from OSC19 cells were implanted subcutaneously into the flank of NSG mice. After ~16 days post injection, tumor formation was observed. Volume of tumor growth was monitored once a week. Data are presented here as the means and standard deviations (*p < 0.01). (b) Representative images of tumors extracted from control and oralspheres injected into NSG mice. (c) A representative tumor section from mice injected with parental and oralspheres from OSC19 cells, stained with hematoxylin and eosin (magnification, 40×) are shown. (d) A representative tumor section from mice injected with parental and oralspheres from OSC19 cells, stained with VEGFR1 (magnification, 40×) are shown.
