Figure 5 | Scientific Reports

Figure 5

From: Novel recombinant chimeric virus-like particle is immunogenic and protective against both enterovirus 71 and coxsackievirus A16 in mice

Figure 5

Cytokine profiles of mice immunized with ChiEV-A71 VLPs.

Cytokines (IFN-γ, IL-2, IL-4 and IL-6) generated by splenocytes collected from mice immunized with VLPs were measured by ELISPOT, following re-stimulation with inactivated EV-A71 (inEV-A71). The number of spot-forming cells (SFC) detected after 48 h of stimulation are shown.

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