Figure 4
From: 3D-DIP-Chip: a microarray-based method to measure genomic DNA damage
Examples of the types of analyses that may be undertaken with 3D-DIP-Chip and ChIP-chip.
Scatter plots show an inverse association between cisplatin and UV induced DNA damage (a) but a positive association between cisplatin and UV induced histone acetylation (c). Plotting the data around transcription start sites (TSSs) shows different patterns of damage induction with the two damaging agents (b; UV solid green line, cisplatin solid black line) along with similar predicted patterns (UV dashed green line, cisplatin dashed black line). Standard errors for all TSSs are shown as a shaded region. Histone acetylation around the same TSSs shows similar patterns with both damaging agents (d; same colouring as b).
