Table 1 Spearman's rank correlation ρ values for 3D-DIP-Chip data of physically and chemically induced DNA damage in human and yeast samples treated in vivo and in vitro. Correlations with prediction are calculated from the predicted profiles created in Sandcastle. Correlations between replicates are calculated from two individual microarray datasets. UV induced DNA damage in yeast was not investigated here.
From: 3D-DIP-Chip: a microarray-based method to measure genomic DNA damage
Human correlations between: | Yeast correlations between: | ||||
|---|---|---|---|---|---|
Treatment | 3D-DIP-Chip and prediction | 3D-DIP-Chip replicates | 3D-DIP-Chip and prediction | 3D-DIP-Chip replicates | |
Cisplatin | In vivo | 0.61 | 0.82 | 0.54 | 0.54 |
In vitro | 0.67 | 0.92 | 0.56 | 0.72 | |
Oxaliplatin | In vivo | 0.40 | 0.74 | 0.53 | 0.55 |
In vitro | 0.41 | 0.59 | 0.51 | 0.55 | |
UV | In vivo | 0.51 | 0.77 | - | - |
In vitro | 0.56 | 0.85 | - | - | |
