Figure 4
From: Optimal microdomain crosstalk between endoplasmic reticulum and mitochondria for Ca2+ oscillations
Ca2+ dynamics modulated by the IP3R-MCU distance.
(a) The spike amplitudes of [Ca2+]Mic (triangles) and [Ca2+]Mt (circles). (b) The spike amplitudes of [Ca2+]Cyt (diamonds) and spike period (spheres). (c) The total amount of Ca2+ released from the ER through IP3Rs during each cycle (squares), the amount of Ca2+ released from the ER through IP3Rs during the rising time (circles) and the fraction delivered to mitochondria through MCU (stars). (d) The spike width (triangles), the rising time (squares) and the decay time (circles) of [Ca2+]Cyt oscillations. [IP3] = 0.5 μM.
