Table 1 Characteristics of the 17 publications included in this meta-analysis
From: Association between PLCE1 rs2274223 A > G polymorphism and cancer risk: proof from a meta-analysis
Study | Country | Ethnicity | Cancer type | Source of controls | Genotyping methods | Sample sizes(Cases/controls) | HWE (controls) | HWE (cases) | Score |
|---|---|---|---|---|---|---|---|---|---|
Ma,2011 | USA | Caucasian | SCCHN | HB | TaqMan | 1097/1089 | 0.977 | 0.234 | 12 |
Zhang,2011 | China | Asian | Gastric | PB | TaqMan | 1665/1848 | 0.451 | 0.664 | 14 |
Bye,2012 | South African | African | ESCC | Mixed | TaqMan | 418/850 | 0.886 | 0.625 | 11 |
South African | Mixed | ESCC | HB | TaqMan | 254/857 | 0.807 | 0.522 | 10 | |
Gu,2012 | China | Asian | ESCC | HB | MassArray | 379/371 | 0.457 | 0.653 | 10 |
Hu,2012 | China | Asian | ESCC | HB | TaqMan | 1061/1211 | 0.577 | 0.975 | 12 |
Li,2012 | China | Asian | Colorectal | HB | MassArray | 231/292 | 0.089 | 0.339 | 9 |
Yang,2012 | China | Asian | Gastric | HB | MassArray | 249/292 | 0.089 | 0.539 | 9 |
Palmer,2012 | Poland | Caucasian | Gastric | PB | TaqMan | 289/376 | 0.307 | 0.964 | 10 |
USA | Caucasian | Gastric | PB | TaqMan | 306/210 | 0.039 | 0.036 | 10 | |
USA | Caucasian | ESCC | PB | TaqMan | 52/210 | 0.039 | 0.579 | 9 | |
USA | Caucasian | EAC | PB | TaqMan | 107/210 | 0.039 | 0.834 | 9 | |
Wang,2012 | China | Asian | Gastric | HB | TaqMan | 1059/1240 | 0.224 | 0.551 | 11 |
Zhou,2012 | China | Asian | ESCC | HB | PCR-LDR | 517/510 | 0.646 | 0.318 | 11 |
Dura,2013 | Netherlands | Caucasian | ESCC | PB | TaqMan | 86/580 | 0.950 | 0.507 | 9 |
Netherlands | Caucasian | EAC | PB | TaqMan | 258/580 | 0.950 | 0.554 | 9 | |
Duan,2013 | China | Asian | ESCC | PB | PCR-RFLP | 381/420 | 0.582 | 0.271 | 11 |
Yuan,2013 | China | Asian | HNC | HB | TaqMan | 501/879 | 0.243 | 0.363 | 12 |
Sharma,2013 | North Indian | Caucasian | GBC | HB | PCR-RFLP | 416/225 | 0.367 | 0.000 | 10 |
Chen,2013 | China | Asian | ESCC | HB | MALDI-TOF MS | 200/300 | 0.210 | 0.895 | 8 |
Wang,2014 | China | Asian | Colorectal | HB | TaqMan | 417/416 | 0.454 | 0.953 | 10 |
Song,2014 | Korean | Asian | Gastric | HB | HRM | 3245/1700 | 0.148 | 0.088 | 11 |
