Table 4 Incidence of acute treatment-related toxicitiesa (n = 27)

From: Concurrent radiotherapy and weekly chemotherapy of 5-fluorouracil and platinum agents for postoperative locoregional recurrence of oesophageal squamous cell carcinoma

 

All patients

CF group (n = 14)

NF group (n = 13)

 
 

n (%)

n (%)

n (%)

P value

Leukocytopenia

    

 Grade 0

4 (14.8)

2 (14.3)

2 (15.4)

1.000

 Grade 1 – 2

17 (63.0)

9 (64.3)

8 (61.5)

 

 Grade 3 – 4

6 (22.2)

3 (21.4)

3 (23.1)

 

Thrombocytopenia

    

 Grade 0

13 (48.1)

9 (64.3)

4 (30.8)

.174

 Grade 1 – 2

13 (48.1)

5 (35.7)

8 (61.5)

 

 Grade 3

1 (3.7)

0 (0.0)

1 (7.7)

 

Anemia

    

 Grade 0

6 (22.2)

4 (28.6)

2 (15.4)

.648

 Grade 1 – 2

20 (74.1)

10 (71.4)

10 (76.9)

 

 Grade 3

1 (3.7)

0 (0.0)

1 (7.7)

 

Nausea and vomiting

    

 Grade 0

0 (0.0)

0 (0.0)

0 (0.0)

1.000

 Grade 1 – 2

26 (96.3)

13 (92.9)

13 (100.0)

 

 Grade 3

1 (3.7)

1 (7.1)

0 (0.0)

 

Oesophagitis

    

 Grade 0

21 (77.8)

10 (71.4)

11 (84.6)

0.648

 Grade 1 – 2

6 (22.2)

4 (28.6)

2 (15.4)

 

Liver enzyme elevation

    

 Grade 0

21 (77.8)

12 (85.7)

9 (69.2)

0.385

 Grade 1 – 2

6 (22.2)

2 (14.3)

4 (30.8)

 
  1. aAcute toxicities were evaluated according to the Common Terminology Criteria for Adverse Events version 3.0 (CTCAE 3.0).