Table 1 Clinical parameters of the study subjects. Data are expressed as mean ± SD. *Represents statistically significant differences (p < 0.05) among non-diabetic control (NDC), pre-diabetes (PD) and type 2 diabetes (T2D). The abbreviations M and F stand for male and female, respectively
Parameters | Non-diabetic control (NDC) (n = 32) | Pre-diabetes (PD) (n = 39) | Type 2 Diabetes (T2D) (n = 48) | p values |
|---|---|---|---|---|
Sex (M/F) | 13/19 | 14/25 | 19/29 | |
Age (Years) | 35.94 ± 7.5 | 34.64 ± 6.5 | 38.6 ± 9.7 | 0.183 |
Weight (kg) | 64.8 ± 6.5 | 65.9 ± 7 | 65.74 ± 5.7 | 0.748 |
BMI (kg/m2) | 24.28 ± 2.8 | 24.17 ± 2.4 | 23.88 ± 2 | 0.877 |
Fasting Plasma Glucose (mg/dL) | 90.19 ± 6.4 | 107.05 ± 5.1 | 140.42 ±7.7 | <0.001* |
Fasting Plasma Insulin (μIU/mL) | 7.26 ± 3.4 | 9.6 ± 2.1 | 23.05 ± 3.2 | <0.001* |
2-hr Post-dose Plasma Glucose (mg/dL) | 123.47 ± 10.1 | 172.56 ± 12.4 | 280.87 ± 39.1 | <0.001* |
HbA1c (%) | 5.27 ± 0.2 | 6.11 ± 0.2 | 7.65 ± 0.5 | <0.001* |
Fasting CA Activity (U/min/mL) | 9.18 ± 1.2 | 8.98 ± 1.2 | 5.81 ± 1.3 | <0.001* |
Post-dose CA Activity (U/min/mL) | 6.47 ± 1.36 | 10.68 ± 1.6 | 11.03 ± 1.8 | <0.001* |
