Table 1 Demographic data and plasma brain-derived neurotrophic factor baseline levels of heroin-dependent patients and healthy controls

From: The BDNF Val66Met polymorphism and plasma brain-derived neurotrophic factor levels in Han Chinese heroin-dependent patients

 

Healthy Controls

Heroin-Dependent Patients

  

Participant Characteristics

n = 102

n = 172

χ2/t/F

p

Gender (M/F)

78/24

141/31

χ2 = 1.21

0.279a

Age (years)

32.1 ± 7.0

37.0 ± 7.3

t = −5.495

<0.0001b

Body weight (kg)

67.2 ± 13.2

66.6 ± 12.6

t = 0.437

0.662b

Plasma BDNF (ng/mL)

18.6 ± 9.4

10.1 ± 7.7

F = 52.28

<0.0001c

Heroin-dependency duration (years)

−

8.2 ± 7.0

  

Methadone oral dose (mg)

−

35.6 ± 21.3

  

Plasma methadone (ng/mL)

−

149.1 ± 167.9

  

Urine test morphine-positive (n)

−

124

  

Urine test methamphetamine-positive(n)

−

28

  
  1. Data are means ± standard deviation (SD). All patient data were compared with data from healthy controls.
  2. BDNF, brain-derived neurotrophic factor.
  3. aχ2 test;
  4. bindependent samples t test;
  5. canalysis of covariance (ANCOVA): covariate = age.
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