Table 3 Plasma brain-derived neurotrophic factor level based on BDNF Val66Met gene variant in heroin-dependent patients and healthy controls

From: The BDNF Val66Met polymorphism and plasma brain-derived neurotrophic factor levels in Han Chinese heroin-dependent patients

BDNF Val66Met

Plasma BDNF (ng/mL)

  

Gene Variant

Healthy Controls

Heroin-Dependent Patients

t

p

Met/Met

19.5 ± 9.2 (n = 26)

10.8 ± 7.0 (n = 49)

4.587

<0.0001a

Met/Val

18.2 ± 9.7 (n = 43)

9.3 ± 7.3 (n = 84)

5.343

<0.0001a

Val/Val

18.5 ± 9.3 (n = 33)

11.1 ± 9.2 (n = 39)

3.362

0.001a

  1. Data are means ± SD.
  2. BDNF, brain-derived neurotrophic factor.
  3. aCompared with healthy controls with the same genotype (Independent samples t test).
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