Table 3 Cumulative effect of the 4 nominally significant SNPs between KD patients and normal controls

From: Systematic Confirmation Study of GWAS-Identified Genetic Variants for Kawasaki Disease in A Chinese Population

No. of non-risk genotypes

KD cases (%)

Controls (%)

OR

95%CI

P †

0

61 (14.88)

49 (10.49)

Ref.

Ref.

 

1

178 (43.41)

181 (38.76)

0.79

0.52–1.22

0.288

2

153 (37.32)

184 (39.40)

0.67

0.43–1.03

0.069

3~4

18 (4.39)

53 (11.35)

0.27

0.14–0.53

<0.001

Cochran-Armitage Trend Test

    

<0.001

  1. Abbreviations: CI, confidence interval; KD, Kawasaki disease; OR, odds ratio.
  2. The 4 nominally significant SNPs were rs1801274, rs3818298, rs2736340 and rs4813003 and the respective non-risk genotypes were GA/GG, CT/CC, CC and TT genotypes.
  3. †All the P values were adjusted for gender. The positive results were in bold.
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