Figure 2
From: Identification of flubendazole as potential anti-neuroblastoma compound in a large cell line screen
Effects of flubendazole in a panel of parental neuroblastoma cell lines and their sub-lines adapted to anti-cancer drugs.
The flubendazole concentrations that decreased cancer cell viability by 90% (IC90) were determined by MTT assay after 5 days of incubation (flubendazole 5 μM was the maximum concentration tested). (a) The average IC90 values for each cancer entity are presented. Error bars represent a single standard deviation. (b) The average IC90 for each cell line (average from 2 experiments per cell line) is presented. (c) The Wilcoxon rank sum test did not indicate a significant difference (p < 0.05) between IC90s for the cell lines with acquired resistance to different drug classes. The detailed data is presented in Suppl Table S2.
