Table 1 Serum chemistry for 18 day-old WT and Cic-L KO mice

From: Deficiency of Capicua disrupts bile acid homeostasis

 

WT

Cic-L KO

No. of tested animals (WT : KO)

Glucose (mg/dL)***

107.0 ± 8.700

53.4 ± 8.235

6:5

Insulin (ng/mL)

0.320 ± 0.026

0.285 ± 0.006

4:4

Cholesterol (µM)

5,137.29 ± 701.646

5,203.03 ± 436.851

4:4

Triglycerides (nmol/µl)

1.477 ± 0.233

0.972 ± 0.017

3:3

Bile acid (µM)**

22.984 ± 3.943

49.309 ± 5.058

6:6

Alanine transaminase (U/L)

39.429 ± 61.849

61.849 ± 11.205

6:6

Total bilirubin (mg/dL)*

0.312 ± 0.044

0.647 ± 0.098

6:6

Direct bilirubin (mg/dL)

0.476 ± 0.128

0.745 ± 0.190

6:6

  1. *p<0.05, **p<0.01, ***p<0.001.
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