Table 1 Results of single point association analysis for the triad family cohort and the case-control cohort and combined meta-analysis

From: Association of genetic variants of GRIN2B with autism

CHR

SNP

BP

A1

A2

MAF

OR.trios

P.trios

OR.cc

P.cc

P.comb

P.adj

12

rs4763351

13686475

A

G

0.488

1.19

0.1545

1.04

0.7677

0.22411

0.32709

12

rs10845801

13691340

A

G

0.292

1.09

0.5169

1.17

0.2324

0.19266

0.29847

12

rs7961819

13698642

G

A

0.201

0.65

0.00845

0.83

0.2526

0.00755

0.0261

12

rs12814951

13700576

A

C

0.217

1.03

0.8332

1.07

0.6342

0.62741

0.69143

12

rs2160517

13705892

A

G

0.494

0.85

0.1987

1

0.9793

0.35384

0.43426

12

rs2193149

13706502

A

G

0.304

1.09

0.5078

1.04

0.771

0.50024

0.57475

12

rs966664

13709208

A

G

0.485

0.88

0.3

0.95

0.6485

0.29133

0.3933

12

rs1806201

13717508

A

G

0.496

1.21

0.1232

1.1

0.4406

0.10199

0.20397

12

rs1806202

13718561

A

C

0.205

1.1

0.5214

1.11

0.465

0.33203

0.41697

12

rs1806213

13723977

C

A

0.21

1.11

0.4773

1.1

0.5007

0.32775

0.41697

12

rs7970177

13738988

A

G

0.192

0.54

0.00039

0.75

0.07802

0.00017

0.005

12

rs1805474

13742150

A

C

0.194

0.67

0.01395

0.71

0.04361

0.00155

0.01673

12

rs888150

13745044

A

G

0.194

0.67

0.01395

0.7

0.03264

0.00116

0.01562

12

rs1805510

13751252

A

C

0.195

0.69

0.02064

0.73

0.06131

0.00308

0.02242

12

rs2268097

13752832

A

G

0.213

0.63

0.00303

0.68

0.0202

0.00018

0.005

12

rs2300238

13813330

A

G

0.205

0.63

0.00376

0.7

0.02959

0.00033

0.00601

12

rs980365

13820027

A

G

0.21

0.67

0.00995

0.81

0.1747

0.0054

0.02242

12

rs2268102

13822239

A

G

0.2

0.67

0.01141

0.81

0.1907

0.00664

0.02563

12

rs2284406

13825416

A

G

0.339

0.67

0.0016

0.97

0.7873

0.01539

0.04375

12

rs1008619

13826407

G

A

0.21

0.65

0.00644

0.82

0.2019

0.00467

0.02242

12

rs918065

13842709

A

G

0.192

0.66

0.01041

0.8

0.1617

0.00509

0.02242

12

rs10845827

13859064

G

A

0.207

0.78

0.1206

0.94

0.6908

0.16793

0.2748

12

rs2284411

13866172

A

G

0.207

1.22

0.1845

1.08

0.6086

0.19345

0.29847

12

rs2300257

13868507

A

G

0.191

1.29

0.09535

1.08

0.6006

0.12125

0.22579

12

rs2268120

13877888

G

A

0.222

1.17

0.2626

1.14

0.3587

0.14954

0.25453

12

rs2216128

13883014

G

A

0.175

0.84

0.2684

0.61

0.00782

0.00773

0.0261

12

rs2192973

13896555

A

G

0.162

0.8

0.1665

0.59

0.00624

0.00359

0.02242

12

rs11055608

13913426

C

A

0.237

1.1

0.4838

1.16

0.2808

0.20848

0.31272

12

rs7301500

13941779

G

A

0.36

0.96

0.7464

0.87

0.2709

0.31384

0.41335

12

rs2284418

13943628

G

A

0.142

1.11

0.5408

1.09

0.6076

0.42628

0.50042

12

rs7974275

13950577

C

A

0.285

1.1

0.4786

1.19

0.1858

0.15083

0.25453

12

rs2300266

13951767

C

A

0.15

0.71

0.05551

0.71

0.07075

0.00849

0.02625

12

rs11055625

13952894

G

A

0.15

0.72

0.05737

0.71

0.07075

0.00875

0.02625

12

rs220573

13956734

G

A

0.452

0.95

0.6374

0.95

0.6761

0.52954

0.59573

12

rs220575

13957286

A

G

0.461

0.97

0.8137

0.97

0.7735

0.71128

0.74921

12

rs220583

13960743

A

G

0.13

1.06

0.7389

1.32

0.0876

0.14886

0.25453

12

rs220597

13968186

A

G

0.13

1.06

0.6451

1.15

0.2899

0.28281

0.39158

12

rs220599

13975298

G

A

0.13

0.93

0.5557

0.92

0.4867

0.36362

0.43634

12

rs2160732

13981326

C

A

0.169

0.7

0.02686

0.72

0.06544

0.00413

0.02242

12

rs2160734

13984349

A

G

0.3

1.21

0.1433

1.11

0.4313

0.11152

0.21507

12

rs2284424

13988870

A

G

0.275

1.21

0.1469

1.14

0.3116

0.08165

0.16957

12

rs2284425

13989019

A

C

0.313

1.3

0.04584

1.11

0.4003

0.04478

0.10513

12

rs2300273

13990434

G

A

0.354

1.31

0.0329

1.07

0.6007

0.0603

0.13308

12

rs1861787

14000568

A

C

0.146

0.68

0.0247

0.72

0.08146

0.0048

0.02242

12

rs2284428

14009914

G

A

0.158

0.68

0.02298

0.71

0.06299

0.00347

0.02242

12

rs10845852

14027137

A

C

0.157

0.82

0.2632

0.72

0.07171

0.03896

0.09563

12

rs10845853

14035011

A

G

0.368

1.08

0.5351

1.12

0.3528

0.27325

0.38831

12

rs10492141

14045250

G

A

0.193

0.72

0.03781

0.87

0.3709

0.03561

0.09158

12

rs10160840

14058573

A

G

0.193

0.73

0.04359

0.91

0.5318

0.06161

0.13308

12

rs918168

14078634

A

G

0.242

0.89

0.4054

0.69

0.01759

0.02338

0.06314

12

rs219876

14081623

A

G

0.102

1.08

0.6976

1.03

0.8639

0.69213

0.7475

12

rs1421108

14131558

G

A

0.398

1.04

0.7694

1

0.9837

0.82451

0.82452

12

rs10845868

14154639

A

C

0.408

1.03

0.8137

1.02

0.8471

0.76191

0.77628

12

rs10772722

14161665

C

A

0.409

1.03

0.8137

1.03

0.7883

0.72146

0.74921

  1. Note: MAF represents minor allele frequency in the Chinese population; P.cc represents P values of the case-control cohort; P.trios represents P values of the trios cohort; P.comb represents P values after meta-analysis; P.adj represents adjusted P values using FDR.
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