Table 3 Common coding variants identified by Sanger sequencing and association results under an additive model

From: Association of genetic variants of GRIN2B with autism

Variants

ExonicFunc

MAF_ESP6500

MAF_1000G

MAF_275case

dbSNP138

OR

P

P.adj

c.C2664T:p.T888T

synonymous

0.216

0.484

0.496

rs1806201

1.05

0.6849

0.6849

c.T4197C:p.H1399H

synonymous

0.168

0.203

0.131

rs1805247

0.59

0.0015

0.0061

c.C1806T:p.I602I

synonymous

0.039

0.187

0.123

rs1805522

0.62

0.0042

0.0083

c.C4218T:p.F1406F

synonymous

0.027

0.077

0.092

rs1805246

1.23

0.3570

0.4760

  1. Note: MAF_1000G only included Chinese samples (CHB and CHD). P.adj represents adjusted P values using FDR.
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