Figure 5
From: SNORD76, a box C/D snoRNA, acts as a tumor suppressor in glioblastoma
SNORD76 expression, rather than its host gene (GAS5), is downregulated in surgically resected glioblastoma (WHO grade IV) tissues.
(A) Compared with glioma tissues of WHO grade II (n = 20) and grade III (n = 22), tissues from glioblastoma (n = 21) displayed lower SNORD76 expression as determined by qPCR. (B) No clinically significant difference in GAS5 expression among tested glioma tissues of WHO grade II, III and IV was detected. *P < 0.05 (ANOVA); ns, no significant difference (P ≥ 0.05) relative to the other group.
