Figure 1
Schematic of preferred microreactor array fill & seal device.
(A) Top view schematic of device consisting of a rigid frame with fasteners clamping a transparent window and transparent sealing membrane onto an O-ring sealing around the perimeter of a microreactor array slide consisting of microreactors with functionalizing chemicals. There are inlet & outlet ports for reagent at the bottom and inlet & outlet ports for sealing liquid at the top. Features are not drawn to scale. (B) Section view schematic of same device illustrating the process of displacing excess reagent and sealing microreactors. After completely filling the microreactors, excess reagent is displaced from the slide by pressurized sealing liquid injected through a sealing liquid inlet port acting on a sealing membrane. As the sealing liquid spreads out across the sealing membrane it first displaces excess reagent though reagent inlet & outlet ports and then seals the microreactors into isolated chemical reaction containers. The schematics (A, B) were drawn by Peter Wiktor.
