Figure 1 | Scientific Reports

Figure 1

From: Excess of Rare Variants in Genes that are Key Epigenetic Regulators of Spermatogenesis in the Patients with Non-Obstructive Azoospermia

Figure 1

The nominally associated genes identified by four different gene-based tests.

(A) Nominally associated gens identified by evaluation of rare non-silent variants in each gene. (B) Nominally associated genes identified by evaluation of both rare and low-frequency non-silent variants in each gene. (C) Nominally associated genes identified by evaluation of rare variants in the UTRs of each gene. (D) Nominally associated genes identified by evaluation of both rare and low-frequency variants in the UTRs of each gene. The height of each bar is proportional to the –log10 P value from the respective gene based test and P values ≥0.05 are not shown in the plots. # indicates the gene was determined to be nominally associated with NOA by at least two different tests.

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