Table 2 The binding constants (KA) (1 × 105) L·mol−1 of the LLO-inhibitors systems based on the fluorescence-quenching method

From: Novel inhibitor discovery and the conformational analysis of inhibitors of listeriolysin O via protein-ligand modeling

 

WT-LLO

Y427A

V428A

S466A

S467A

Myr

4.21

1.97

2.05

2.14

2.34

Mor

3.98

2.04

1.98

1.91

2.01

Bac

3.84

1.89

1.88

1.84

1.86

Chr

3.59

1.81

1.90

1.77

1.84

Nar

3.14

1.74

1.84

1.69

1.71

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