Figure 3
From: Human iPSC-based Cardiac Microphysiological System For Drug Screening Applications
Cardiac tissue derived from a genetically engineered hiPS cell line expressing a GCaMP6 reporter in the MPS.
(a) Frames from a fluorescence movie (GFP channel) showing the switching from dim to bright during activity of Ca2+ channels. (b) Time-course of the normalized fluorescence intensity (green) and the beating motion (red) obtained by computational analysis of the movie. This combination allows high throughput analysis of mechanical and electrophysiological properties.
