Figure 6
From: Photothermal cellular stimulation in functional bio-polymer interfaces
Numerical simulations of the membrane potential responses to photostimulation.
(a,b) Statistical distribution for the parameters αC (a) and αV (b) of the numerical model obtained from the fitting of the experimental curves (n = 54 cells). (c,d) Simulated time evolution (solid blue lines) of the membrane resistance (c) and membrane capacitance (d) for typical values of the model parameters (αC = 0.0032, αV = 0.375), compared to the values measured from Fig. 5 (shaded grey regions). (e,f) Comparison between the membrane potential experimental measurements (grey dots) and numerical simulation (magenta lines) for a typical cell under photoexcitation with 20 ms (e) and 200 ms (f) pulses (cyan rectangles). Dashed lines represent the calculated contributions to the final potential traces from the variation in membrane capacitance (blue) and reversal potential (green).
