Figure 3
From: Prevention of exercised induced cardiomyopathy following Pip-PMO treatment in dystrophic mdx mice
Gene expression analysis for markers of cardiac injury in exercised mdx mice following Pip6f-PMO treatment.
RT-qPCR analysis of Nppa (A) and Nox4 (B) in heart tissue normalised to C57BL/10 cohort. The untreated mdx exercised cohort reveals elevated expression of these injury markers whereas there is partial normalisation for the Pip6f-PMO cohort. Statistical significance was determined using ANOVA followed by Tukey post-hoc test (*** = P < 0.001, ** = P < 0.01, * = P < 0.05).
