Figure 6
From: Quercetin Attenuates Lactate Production and Extracellular Matrix Secretion in Keratoconus
Quantification of western blots of HCF and HKC cell lysates following four week treatment with or without Quercetin and/or Lactate treatment.
(A) TGF-βRII expression was significantly up regulated in HCFs following lactate stimulation (p < 0.05) and down regulated in HKCs following Quercetin stimulation (p < 0.05), (B) TGF-β2 expression was significantly up regulated in HKCs following Lactate stimulation (p < 0.05) where HCFs showed no differences. Quercetin stimulation led to significant down regulation of TGF-β2 expression in both HCFs and HKCs. All gels have been run under the same experimental conditions. n = 3, error bars represent SEM.
